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Home 9 News Item 9 Wiggin and Dana Advises Affibody AB in Collaboration with Alexion Pharmaceuticals, Inc.

Wiggin and Dana Advises Affibody AB in Collaboration with Alexion Pharmaceuticals, Inc.

March 20, 2019

Wiggin and Dana LLP advised client Affibody AB, a private clinical-stage Swedish biotech company, in a collaboration with Alexion Pharmaceuticals, Inc. to co-develop ABY-039 for rare Immunoglobulin G (IgG)-mediated autoimmune diseases. Currently in Phase 1 development, ABY-039 is a bivalent antibody-mimetic that targets the neonatal Fc receptor (FcRn). ABY-039 has been specifically designed to combine Affibody’s protein therapeutics platform (Affibody® molecules) and Albumod™ technology to achieve a long half-life, which, along with its small size provides the potential for less frequent, convenient, at-home subcutaneous administration.

Under the terms of the Agreement, Affibody is eligible to receive up to $650 million in upfront payments, and development and sales milestones, and tiered low double-digit royalties. Affibody retained the rights to lead clinical development of ABY-039 in an undisclosed indication and has the option to co-promote ABY-039 in the United States. The transaction is subject to clearance under the Hart-Scott-Rodino Antitrust Improvements Act.

Wiggin and Dana Partner, Patti Melick, and Senior Associate, Monica Kolinsky, served as lead counsel on the transaction.

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